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Index > Protein center > ANPEP(Gene name) > Chicken
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  • ANPEP (Gene name),
  • Aminopeptidase N (Protein name ),  AMPN_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ANPEP(APDE);
    Protein name:
    Aminopeptidase N;
    Alternative:
    3.4.11.20;Aminopeptidase Ey);
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Broad specificity aminopeptidase. Degrades a variety of peptides possessing various N-terminal amino acids including hydrophobic, basic and acidic amino acids. Preferentially hydrolyzes small peptides consisting of 4 or 5 amino acids. Hydrolyzes the N-terminal Xaa-Pro bonds in the chicken brain peptide Leu-Pro-Leu-Arg-PheNH2, the substance P fragment Arg-Pro-Lys-Pro and the bradykinin fragment Arg-Pro-Pro-Gly-Phe. Hydrolyzes the N-formylated peptides fMet-Leu-Phe, fMet-Ala-Gly-Ser-Glu and fMet-Nle-Leu-Phe-Nle-Tyr-Lys, but does not hydrolyze peptides with acetylation or pyroglutamic acid at N-terminus. Does not hydrolyze large peptides such as complete substance P, bradykinin or schistoFLRFamide.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein A soluble form has also been detected.
    Protein Attributes:
    Sequence length:
    967
    Sequence:
    50:
    MAAGFFISKS | VGIVGIVLAL | GAVATIIALS | VVYAQEKNKS | SGGSGGSDTT | 
    100:
    STTTASTTTA | STTAAPNNPW | NRWRLPTALK | PESYEVTLQP | FLTPDDNNMY | 
    150:
    IFKGNSSVVF | LCEEATDLIL | IHSNKLNYTL | QGGFHASLHA | VNGSTPPTIS | 
    200:
    NTWLETNTQY | LVLQLAGPLQ | QGQHYRLFSI | FTGELADDLA | GFYRSEYTEG | 
    250:
    NVTKVVATTQ | MQAPDARKAF | PCFDEPAMKA | VFTVTMIHPS | DHTAISNMPV | 
    300:
    HSTYQLQMDG | QSWNVTQFDP | TPRMSTYLLA | FIVSQFDYVE | NNTGKVQIRI | 
    350:
    WGRPAAIAEG | QGEYALEKTG | PILSFFERHY | NTAYPLPKSD | QVGLPDFNAG | 
    400:
    AMENWGLVTY | RENSLLYDNA | YSSIGNKERV | VTVIAHELAH | QWFGNLVTLR | 
    450:
    WWNDLWLNEG | FASYVEYLGA | DSAEPTWDIK | DLMVLNELYT | VMATDALTTS | 
    500:
    HPLTFREDEI | NTPAQISEVF | DSIAYSKGAS | VLRMLSDFLT | EDVFKEGLQS | 
    550:
    YLHDFSYNNT | VYTDLWDHLQ | EAVNKNSVPL | PDSIGAIMDR | WTLQMGFPVV | 
    600:
    TVNTLTGSVQ | QSHFLLDSNS | TVERPSVFNY | TWIVPITWMT | PSRTGDRYWL | 
    650:
    VDVSATNSNF | SVGSSTWLLL | NLNVSGYFRV | NYNQENWDQL | LQQLSNNHQA | 
    700:
    IPVINRAQII | DDAFNLARAH | NVNVTLALNT | TRFLSGETAY | MPWQAALNNL | 
    750:
    QYFQLMFDRS | EVFGAMTKYI | QKQVTPLFEY | YRTATNNWTA | IPSALMDQYN | 
    800:
    EINAISTACS | YGIAECQQLA | TALYQQWRQN | VSNNPIAPNL | RSAIYCSAVA | 
    850:
    TGGEEVWDFI | WERFLEAPVV | SEADKLRTAL | TCSTETWILQ | RYLQYTIDPT | 
    900:
    KIRKQDATST | INSIASNVVG | QPLAWDFIRS | NWRTLFGQYG | GGSFSFSRLI | 
    950:
    SAVTQRFNTE | FELKQLEHFK | ADNQDIGFGS | GTRALEQALE | RTRTNINWVK | 
    967:
    ENKEVVHAWF | RAETASS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    UniGene:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154m
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    96T
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    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154p
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    96T
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    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154c
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    Please sign in first.
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    96T
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    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154r
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    96T
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    ELISA Kit for Chicken Aminopeptidase N
    MSDS:
    Please sign in first.
    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Chicken Aminopeptidase N
    Cat.:
    E9154b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Chicken Aminopeptidase N
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Aminopeptidase N
    Cat.:
    U9154c
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Chicken Aminopeptidase N
    Polyclonal Antibody for Chicken Aminopeptidase N
    Polyclonal Antibody for Chicken Aminopeptidase N
    Polyclonal Antibody for Chicken Aminopeptidase N
    Cat.:
    P9154Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Aminopeptidase N
    Polyclonal Antibody for Chicken Aminopeptidase N
    Polyclonal Antibody for Chicken Aminopeptidase N
    Cat.:
    P9154Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Aminopeptidase N
    Cat.:
    P9154Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Monoclonal Antibody for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N
    Protein for Chicken Aminopeptidase N

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and characterization of cDNA encoding chicken egg yolk aminopeptidase Ey."
      Midorikawa T. , Abe R. , Yamagata Y. , Nakajima T. , Ichishima E.
      Comp. Biochem. Physiol.119:513-520(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 219-229; 296-363; 378-405; 496-526 AND 954-966
      tissue: Egg yolk.
      tissue: Liver.
    2. 2.
      "Soluble high-expression and biological function of chicken aminopeptidase N."
      Xin Y. , Ping W. , Bo M.X.
      Submitted (2009-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Embryonic kidney.
    3. 3.
      "Soluble and bound forms of aminopeptidase in hen's egg yolk."
      Ichishima E. , Yamagata Y. , Chiba H. , Sawaguchi K. , Tanaka T.
      Agric. Biol. Chem.53:1867-1872(1989)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    4. 4.
      "Electron microscopic analysis of dimeric form of aminopeptidase Ey from hen's egg yolk."
      Tanaka T. , Oshida K. , Ichishima E.
      Agric. Biol. Chem.55:2179-2181(1991)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    5. 5.
      "Substrate specificity of aminopeptidase Ey from hen's (Gallus domesticus) egg yolk."
      Tanaka T. , Ichishima E.
      Comp. Biochem. Physiol.105:105-110(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
    6. 6.
      "Molecular properties of aminopeptidase Ey as a zinc-metalloenzyme."
      Tanaka T. , Ichishima E.
      Int. J. Biochem.25:1681-1688(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COFACTOR
    7. 7.
      "Inactivation of chemotactic peptides by aminopeptidase Ey from hen's (Gallus gallus domesticus) egg yolk."
      Tanaka T. , Ichishima E.
      Comp. Biochem. Physiol.107B:533-538(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
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